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Search Results for " immune response "

81

抑制剂 & 化合物

13

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T6828	ZL0420	Epigenetic Reader Domain	Chromatin/Epigenetic
	ZL0420 是有效且选择性的 BET 溴结构域 4 (BRD4) 抑制剂，对 BRD4 的溴结构域 (BD) 具有纳摩尔结合亲和力。ZL0420 对 BRD4 BD1和 BRD4 BD2 的IC50分别为 27 nM 和 32 nM。
T6859	I-BRD9 GSK602	Epigenetic Reader Domain	Chromatin/Epigenetic
	I-BRD9 (GSK602) 是一种选择性的 BRD9 细胞抑制剂，pIC50 为 7.3。
T3146	BMS-202 PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2	Apoptosis; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	BMS-202 (PD1-PDL1 inhibitor 2) 是一种非肽类 PD-1/PD-L 复合物抑制剂，其 IC50为 18 nM，KD 为 8 μM。它与 PD-L1 直接结合并阻断人类 PD-1/PD-L 的相互作用，具有抗肿瘤活性。
TP1029	Thymalfasin 胸腺法新,Thymosin α1,醋酸胸腺α1	Others	Others
	Thymalfasin (Thymosin α1) 是一种免疫调节化合物，可增强 Thl 的免疫应答。
T21444	Diphenylcyclopropenone DPCP,Diphencyprone,二苯基环丙烯酮	Others	Others
	Diphenylcyclopropenone (DPCP) 是局部免疫调节剂，可用于研究斑秃。
T10389L	Aspartyl-alanyl-diketopiperazine acetate DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base)	Others	Others
	Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) 可以通过与 T 淋巴细胞无反应有关的分子途径调节炎症免疫反应。
T74140	β-D-Glucan	Others	Others
	β-D-Glucan 是一种靶向肿瘤相关巨噬细胞的化合物，具有抗肿瘤活性，可调节坏死性胰腺炎中的免疫反应
T0944	Levamisole hydrochloride (-)-Tetramisole hydrochloride,盐酸左旋咪唑	Phospholipase; AChR; Parasite; HSV	Metabolism; Microbiology/Virology; Neuroscience
	Levamisole hydrochloride ((-)-Tetramisole hydrochloride) 是驱虫剂和免疫调节剂。它对HSV 病毒有明显抗病毒作用。
T0134	Imiquimod 咪喹莫特,R 837,S-26308	SARS-CoV; TLR; Autophagy; HSV	Autophagy; Immunology/Inflammation; Microbiology/Virology
	Imiquimod (R 837) 是一种免疫反应修饰剂，可作为 toll 样受体7 激动剂。它有抗病毒和抗肿瘤作用，可研究外生殖器、肛周疣、癌症和 COVID-19。
T9107	NP-G2-044	Others	Others
	NP-G2-044 是fascin 蛋白抑制剂，具有口服活性，IC50值约为 2 μM。它可阻断肿瘤转移并增强抗肿瘤免疫应答。
T23371	SMER3 SMER 3	Others; Ligand for E3 Ligase	Others; PROTAC
	SMER3 是选择性的 Skp1-Cullin-F-box (SCF)Met30泛素连接酶抑制剂。SMER 3 通过抑制 SCFMet30来增强 Rapamycin 的生长抑制作用。
T78525	IRG1-IN-1	Others	Others
	IRG1-IN-1为衣康酸衍生物，具有抑制免疫反应基因1(IRG1)活性的能力，适用于癌症、炎症及自身免疫性疾病的研究领域。
T73133	FGF22-IN-1	Others	Others
	FGF22-IN-1 是一种潜在的 CD4 N-末端免疫球蛋白可变区样结构域（CD4 D1）抑制剂。FGF22-IN-1 可抑制CD4 与主要组织相容性复合体（MHC） II 类蛋白之间的相互作用，抑制免疫应答。
T50107	ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate	Others	Others
	ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate 是一种合成化合物，属于姜黄素家族。它通过抑制NF-κB 信号通路参与免疫反应和炎症的调节，通过激活Nrf2信号通路参与抗氧化反应的调节，通过抑制Akt 信号通路参与细胞存活和增殖的调节。
T6964	Resiquimod R848,雷西莫特,S28463	HCV Protease; TLR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Resiquimod (R848) 是一种 Toll 样受体7/8的激动剂，可诱导细胞因子上调。
T77635	LSD1-IN-27	Histone Demethylase; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation
	LSD1-IN-27 是一种高效的 LSD1 抑制剂，IC50 值为 13 nM。LSD1-IN-27 对胃癌细胞的干细胞性和迁移有抑制作用。LSD1-IN-27 对 BGC-823 和 MFC 细胞中 PD-L1 的表达有抑制作用。LSD1-IN-27 可增强对胃癌的 T 细胞免疫反应。
T7055	Bz-RS-ISer(3-Ph)-Ome Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) 是紫杉醇衍生物，在低细胞毒性下抑制 HSV 复制周期，阻断 Vero 细胞的有丝分裂，影响 M-MSV 诱导的肿瘤大小，并通过抑制 PHA 诱导的 T 淋巴细胞增殖而影响免疫应答。
T74485	STC314	Others	Others
	STC314 具有抗感染作用，通过中和胞外组蛋白和中性粒细胞诱捕网来逆转机体过度免疫反应造成的器官损伤，可用于研究脓毒症和急性呼吸窘迫综合征(ARDS)。STC314 可保护脂质双层的稳定性，抑制血小板活化和红细胞损伤。
T19468	Nafocare B1 Methylfurylbutyrolactone	Others	Others
	Nafocare B1 is a modifier of synthetic immune biological response.
T74760	Polyinosinic acid
	Polyinosinic acid, a single-stranded homonucleic acid and a Toll-like Receptor 3 (TLR3) agonist, enhances the cellular immune response through TLR3 and TRIF. It holds potential applications in immune regulation [1].
T70594	Gliotoxin monoacetate
	Gliotoxin monoacetate is a toxin found in Aspergillus. It induces apoptosis in cervical cancer cells and chondrosarcoma cells, suppresses the adaptive immune response in leukocytes, and inhibits the proteasome in Plasmodium falciparum.
T22862	Imiquimod maleate	Others	Others
	Imiquimod maleate is an immune response modifier. It acts as a toll-like receptor 7 agonists and is commonly used topically to treat warts on the skin of the genital and anal areas.
T40473	rCRAMP (rat)
	rCRAMP (rat), the rat cathelin-related antimicrobial peptide, plays a crucial role in the antibacterial activity found in rat brain peptide/protein extracts. As a potential key player in the innate immune system of the rat central nervous system, rCRAMP (rat) serves to enhance immune response.
T39187	Gliadin p31-43 Gliadin p31-43
	Gliadin p31-43, an undigested peptide derived from gliadin, prompts an innate immune response in the intestine and disrupts endocytic trafficking. Moreover, its utilization in celiac disease research has proven beneficial.
T83842	LHC165 hydrate
	LHC165是一种对Toll样受体7（TLR7）具有激动作用的化合物。
T80962	TPNQRQNVC LRH-1 peptide
	TPNQRQNVC为HLA-B0702的九肽抗原决定簇，能激活CD8+ T细胞的免疫响应。
T36595	4-epi-Chlortetracycline (hydrochloride)
	Chlortetracycline is an analog of tetracycline , a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response. 4-epi-Chlortetracycline is an epimer of chlortetracycline.
T82925	Baloramotide
	Baloramotide，一种重组蛋白，包含182个氨基酸，源自NY-ESO-1。该化合物能够促进免疫系统对肿瘤的响应。
T74701	A18-Iso5-2DC18
	A18-Iso5-2DC18（compound A18）为环状类可电离阳离子脂质，具促进mRNA蛋白表达及诱导强烈介导免疫反应功能。
T11701	J22352	Caspase	Apoptosis; Proteases/Proteasome
	J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects in glioblastoma by promoting HDAC6 degradation. It does so by inhibiting autophagy and stimulating the antitumor immune response, further restoring host antitumor activity through the reduction of PD-L1's immunosuppressive activity.
T31963	Glyco-lipid Glycolipid,Glyco lipid
	Glycolipids are lipids with a carbohydrate attached by a glycosidic (covalent) bond. Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response and in the connections that allow cells to connect to one another to form tissues.
T72830	TLR8 agonist 5
	TLR8 agonist5 是有效的 TLR8激动剂，对 HEK-Blue hTLR8 的 EC50值为 20 nM。TLR8 agonist5 激活免疫反应。
T25749	L-NIL dihydrochloride L-NIL HCl,N-Iminoethyl-L-lysine dihydrochloride
	L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response
T68594	NFAT:AP-1 inhibitor-10
	NFAT:AP-1 inhibitor-10 is a novel inhibitor of the NFAT:AP-1:DNA interaction on the ARRE-2 element, binding to DNA in a sequence-selective manner and inhibiting the transcription of the Il2 gene and several other cyclosporin A-sensitive cytokine genes important for the effector immune response.
T70268	3A-MPLA
	Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL)-1β, however not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection.
T36984	Cyclic di-IMP (sodium salt)
	Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP . C-di-IMP has adjuvant properties when co-administered with antigens in vitro and by mucosal routes in vivo. C-di-IMP enriches the population of MHC class I and II, CD80, CD86, CD40, and CD54 positive dendritic cells derived from murine bone marrow. It also stimulates macrophages at 500 ng/ml. Mice immunized with β-galactosidase (β-gal) p...
T78198	DRI-C21041 (DIEA)
	DRI-C21041 (DIEA)是一种IC50值为0.31 μM的CD40/CD40L相互作用抑制剂，能够抑制同种异体抗原诱导的免疫反应。
T81114	Spns2-IN-1	LPL Receptor	GPCR/G Protein
	Spns2-IN-1，作为一种Spns2依赖性S1P转运(Spns2)的有效抑制剂，其IC50值为1.4±0.3 μM，对免疫反应有着显著影响<sup>[1]。
T82381	Fmoc-Thr(GalNAc(Ac)3-β-D)-OH
	Fmoc-Thr(GalNAc(Ac)3-β-D)-OH 通过抑制癌细胞生长及增强免疫反应的方式，针对特定癌症途径发挥作用。
T79193	DRI-C21041
	DRI-C21041，作为一种针对CD40/CD40L相互作用的抑制剂，其IC50为0.31 μM，能够抑制由同种异体抗原诱导的免疫反应。
T78019	Nangibotide TFA LR12 TFA
	Nangibotide TFA为TREM-1受体抑制剂，调控先天免疫反应。该化合物能降低啮齿动物心肌缺血再灌注模型的系统性及局部炎症。
T81707	Nangibotide LR12
	Nangibotide为TREM-1受体抑制剂，具有调节先天免疫反应的作用。在啮齿动物心肌缺血再灌注模型中，Nangibotide能有效减轻全身及原位的炎症反应。
T62254	TLR9-IN-1
	TLR9-IN-1 是一种选择性的、有效的 TLR9 抑制剂，能够作用于人 TLR9 (IC50: 7 nM)。TLR9-IN-1 能够用于不良免疫应答相关疾病的研究。
T79194	DRI-C25441
	DRI-C25441, 作为一种CD40与CD40L相互作用的有效阻断剂，其IC50为0.36 μM，能够抑制同种异体抗原诱导的免疫反应。
T82311	Gliadin p31-43 TFA
	Gliadin p31-43 TFA 是一种未消化gliadin peptide，可诱导肠道先天性免疫反应并干扰内吞运输，用于乳糜泻研究。
T38283	Tetracosanoyl-sulfatide C24 3'-sulfo Galactosylceramide (d18:1/24:0)
	Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of Tetracosanoyl-sulfatide are elevated in plasma derived from patients with metachromatic leukodystrophy, a disorder characterized by arylsulfatase A deficiency, leading to sulfatide accumulation. Unlike C24:1 3'-sulfo galactosylceramide, it does not induce an immune response in mo...
T27192	DMI-9523 DA-DKP,Ampion,DMI 9523,DM-9523
	DMI-9523 is nuclear factor NF-κB activation inhibitor. Antigen-stimulated human T lymphocytes produce significantly lower quantities of interferon-gamma and tumor necrosis factor-alpha after stimulation in vitro in the presence of DA-DKP. DA-DKP can modul
T22091	Imiquimod hydrochloride
	Imiquimod hydrochloride (R 837 hydrochloride)是一种免疫反应调节剂，是一种选择性的 toll 样受体 7 (TLR7) 激动剂。Imiquimod hydrochloride 在体内表现出抗病毒和抗肿瘤作用。Imiquimod hydrochloride 可用于外生殖器、肛周疣、癌症和 COVID-19 的研究。
T78755	PD-1/PD-L1-IN-31	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	PD-1/PD-L1-IN-31为具高效PD-1/PD-L1抑制能力的化合物（IC50=2.2 nM），能激进IFN-γ分泌及激活外周血单核细胞（PBMC），进而抑制肿瘤细胞生长。
T71180	Oglufanide disodium
	Oglufanide disodium is t he disodium salt of a synthetic form of a naturally-occurring dipeptide consisting of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating activities. Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis. This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections. Check for active clinical trials or closed clinical trials u...

化合物

Cat.No: T6828

Target: Epigenetic Reader Domain

Cat.No: T6859

Synonym: GSK602

Target: Epigenetic Reader Domain

Cat.No: T3146

Synonym: PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2

Target: Apoptosis, PD-1/PD-L1

Cat.No: TP1029

Synonym: 胸腺法新,Thymosin α1,醋酸胸腺α1

Target: Others

Diphenylcyclopropenone

Cat.No: T21444

Synonym: DPCP,Diphencyprone,二苯基环丙烯酮

Target: Others

Aspartyl-alanyl-diketopiperazine acetate

Cat.No: T10389L

Synonym: DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base)

Target: Others

Cat.No: T74140

Target: Others

Levamisole hydrochloride

Cat.No: T0944

Synonym: (-)-Tetramisole hydrochloride,盐酸左旋咪唑

Target: Phospholipase, AChR, Parasite, HSV

Cat.No: T0134

Synonym: 咪喹莫特,R 837,S-26308

Target: SARS-CoV, TLR, Autophagy, HSV

Cat.No: T9107

Target: Others

Cat.No: T23371

Synonym: SMER 3

Target: Others, Ligand for E3 Ligase

Cat.No: T78525

Target: Others

Cat.No: T73133

Target: Others

ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate

Cat.No: T50107

Target: Others

Cat.No: T6964

Synonym: R848,雷西莫特,S28463

Target: HCV Protease, TLR

Cat.No: T77635

Target: Histone Demethylase, PD-1/PD-L1

Bz-RS-ISer(3-Ph)-Ome

Cat.No: T7055

Synonym: Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

Target: Others, HIV Protease

Cat.No: T74485

Target: Others

Cat.No: T19468

Synonym: Methylfurylbutyrolactone

Target: Others

Polyinosinic acid

Cat.No: T74760

Gliotoxin monoacetate

Cat.No: T70594

Imiquimod maleate

Cat.No: T22862

Target: Others

Cat.No: T40473

Cat.No: T39187

Synonym: Gliadin p31-43

Cat.No: T83842

Cat.No: T80962

Synonym: LRH-1 peptide

4-epi-Chlortetracycline (hydrochloride)

Cat.No: T36595

Cat.No: T82925

Cat.No: T74701

Cat.No: T11701

Target: Caspase

Cat.No: T31963

Synonym: Glycolipid,Glyco lipid

Cat.No: T72830

L-NIL dihydrochloride

Cat.No: T25749

Synonym: L-NIL HCl,N-Iminoethyl-L-lysine dihydrochloride

NFAT:AP-1 inhibitor-10

Cat.No: T68594

Cat.No: T70268

Cyclic di-IMP (sodium salt)

Cat.No: T36984

DRI-C21041 (DIEA)

Cat.No: T78198

Cat.No: T81114

Target: LPL Receptor

Fmoc-Thr(GalNAc(Ac)3-β-D)-OH

Cat.No: T82381

Cat.No: T79193

Nangibotide TFA

Cat.No: T78019

Synonym: LR12 TFA

Cat.No: T81707

Synonym: LR12

Cat.No: T62254

Cat.No: T79194

Gliadin p31-43 TFA

Cat.No: T82311

Tetracosanoyl-sulfatide

Cat.No: T38283

Synonym: C24 3'-sulfo Galactosylceramide (d18:1/24:0)

Cat.No: T27192

Synonym: DA-DKP,Ampion,DMI 9523,DM-9523

Imiquimod hydrochloride

Cat.No: T22091

PD-1/PD-L1-IN-31

Cat.No: T78755

Target: PD-1/PD-L1

Oglufanide disodium

Cat.No: T71180

Cat. No.	Product Name	Target	Signaling Pathways
T4940	3-Methylhistamine dihydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	3-Methylhistamine dihydrochloride 是一种组胺的降解产物，与免疫反应有关，并在接种过疫苗的小鼠中表现出上调作用。
T14063	7α,25-Dihydroxycholesterol 7α,25-OHC	EBI2/GPR183; Endogenous Metabolite	GPCR/G Protein; Metabolism
	7α,25-Dihydroxycholesterol 是一种孤儿 GPCR 受体EBI2 (GPR183)的内源性配体和有效选择性激动剂。它对激活 EBI2 有很强的作用 (EC50=140 pM;Kd=450 pM)。它能够作为一种趋化因子，指导 B 细胞、T 细胞和树突状细胞的迁移。
T34295	Resiniferatoxin RTX,[3H]resiniferatoxin,树脂毒素	IL Receptor	Immunology/Inflammation
	Resiniferatoxin ([3H]resiniferatoxin) 抑制 Th1 细胞因子的产生，有助于防御 T.spiralis 感染，并可用于免疫反应调节剂的研究。
T4A2462	Telocinobufagin Telobufotoxin,远华蟾蜍精,Telocinobufogenin	Others	Others
	Telocinobufagin (Telobufotoxin) 是一种从蟾酥中分离提取获得的组份。
T5S0993	Kurarinone 苦参酮,苦参黄素	BCL; Others; IκB/IKK; TNF; NF-κB; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; Others; Stem Cells
	Kurarinone 是从灌木苦参中提取的黄酮类化合物，具有抗肿瘤、雌激素和抗炎活性，对免疫反应也有很强的抑制作用。
T11855	Lipopolysaccharides 脂多糖,LPS	Others	Others
	Lipopolysaccharides (LPS) 属于天然产物，是一种来源于革兰氏阴性菌外膜外叶的内毒素。Lipopolysaccharides 是一种高免疫原性抗原，可以增强免疫反应，可以用于炎症模型构建。
T10065L	2',3'-cGAMP sodium 2'-3'-cyclic GMP-AMP sodium	STING; cGAS	Immunology/Inflammation
	2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) 是一种cGAMP 合成酶(cGAS)影响细胞质DNA 产生的第二信使，是一种跨膜衔接蛋白，是细胞对致病性细胞质DNA 的先天免疫反应的关键组成部分。
T1183	Retinol all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin	Others	Others
	Retinol (Alphalin) 及其衍生物，在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。膳食维生素 A 来源于植物中发现的多种类胡萝卜素。它富含肝脏、蛋黄和乳制品的脂肪成分。
T4S1469	Cucurbitacin IIb 葫芦素IIB,雪胆素乙	Apoptosis; Others	Apoptosis; Others
	Cucurbitacin IIb 是一种雪胆中的活性成分。它阻碍 STAT3，JNK 和 Erk1/2 的磷酸化，提高 IκB 和 NF-κB (p65) 的磷酸化水平，抑制 NF-κB (p65) 的核转位，降低 IκBα 和 TNF-α 的 mRNA 水平。它能够诱导细胞凋亡，具有抗炎作用。
T2563	Acetyl-L-carnitine hydrochloride Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,乙酰-L-肉(毒)碱盐酸盐,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) 是一种由内源性左旋肉碱的乙酰化形式的盐酸盐组成的营养补充剂，具有潜在的神经保护、认知增强、抗抑郁和免疫调节活性。还可缓解化疗、糖尿病或其他疾病引起的周围神经病变。此外，乙酰左旋肉碱可能通过增加T淋巴细胞成熟来调节免疫反应，并可能下调促炎细胞因子对病毒(如SARS-CoV-2)的反应。它还可能破坏ACE2信号通路并抑制活性氧(ROS)的产生。
T3S1612	kuwanon G 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G	Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂，具有杀菌作用。
T7009	Soyacerebroside II	IL Receptor; Calcium Channel	Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism
	Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral blood mononuclear cells (PBMC).
T13606L	cGAMP disodium
	cGAMP disodium 是在细菌中发现的一种环二核苷酸 (CDN) ，可作为内源性第二信使，影响干扰素的产生以响应胞浆 DNA。cGAMP disodium 通过激活干扰素基因刺激因子 (STING)使 I 型干扰素和其他免疫介质的信号产生级联现象。cGAMP disodium 是一种有效的舌下免疫佐剂，能使免疫功能（血清抗 PA 中和和气道分泌物抗 PA SIgA 反应）更好的发挥作用。

天然产物

3-Methylhistamine dihydrochloride

Cat.No: T4940

Target: Others, Endogenous Metabolite

7α,25-Dihydroxycholesterol

Cat.No: T14063

Synonym: 7α,25-OHC

Target: EBI2/GPR183, Endogenous Metabolite

Resiniferatoxin

Cat.No: T34295

Synonym: RTX,[3H]resiniferatoxin,树脂毒素

Target: IL Receptor

Telocinobufagin

Cat.No: T4A2462

Synonym: Telobufotoxin,远华蟾蜍精,Telocinobufogenin

Target: Others

Cat.No: T5S0993

Synonym: 苦参酮,苦参黄素

Target: BCL, Others, IκB/IKK, TNF, NF-κB, JAK, STAT

Lipopolysaccharides

Cat.No: T11855

Synonym: 脂多糖,LPS

Target: Others

2',3'-cGAMP sodium

Cat.No: T10065L

Synonym: 2'-3'-cyclic GMP-AMP sodium

Target: STING, cGAS

Cat.No: T1183

Synonym: all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin

Target: Others

Cucurbitacin IIb

Cat.No: T4S1469

Synonym: 葫芦素IIB,雪胆素乙

Target: Apoptosis, Others

Acetyl-L-carnitine hydrochloride

Cat.No: T2563

Synonym: Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,乙酰-L-肉(毒)碱盐酸盐,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride

Target: Others, Endogenous Metabolite

Cat.No: T3S1612

Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Soyacerebroside II

Cat.No: T7009

Target: IL Receptor, Calcium Channel

Cat.No: T13606L

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